颅咽管瘤放疗后发生的恶性星形细胞瘤。
Malignant astrocytoma following radiotherapy for craniopharyngioma.
作者信息
Menon G, Nair S, Rajesh B J, Rao B R M, Radhakrishnan V V
机构信息
Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
出版信息
J Cancer Res Ther. 2007 Jan-Mar;3(1):50-2. doi: 10.4103/0973-1482.31974.
Radiation induced gliomas are uncommon. Occurrence of glioma following radiotherapy for craniopharyngiomas is extremely uncommon and only eight case reports have been so far published. We present our experience with one similar case of temporal gliomas occurring twelve years following radiotherapy for a sub totally excised craniopharyngioma. Although the exact mechanism of gliomas formation is unclear, their occurrence following conventional radiotherapy is a distinct possibility and signifies a poor prognosis.
放射性诱发的胶质瘤并不常见。颅咽管瘤放疗后发生胶质瘤极为罕见，迄今为止仅发表了8例病例报告。我们介绍了1例类似病例，该颞叶胶质瘤发生于次全切除颅咽管瘤放疗12年后。虽然胶质瘤形成的确切机制尚不清楚，但在传统放疗后发生胶质瘤是一种明显的可能性，且预示着预后不良。
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