Coscarón Blanco Enrique, Zamora Martínez Tomás, Pérez Liedo María Cruz, Suárez Ortega María Soledad, Blanco García José Luis
Servicio de Otorrinolaringología, Hospital Virgen de la Concha, Zamora, España.
Acta Otorrinolaringol Esp. 2007 Nov;58(9):440-4.
Castleman's disease is an uncommon benign lymphoid disorder usually found in the mediastinum (70 %) which is thought to be due to antigenic hyperstimulation of unknown origin. Two histological subtypes may be found in relation to two different clinical patterns with clinical and therapeutic implications. Diagnosis is frequently accomplished only by histological analysis after surgery since no specific features have been found in imaging studies. Surgical excision is both diagnostic and curative in localized forms, whereas additional therapies are required in multicentric forms. This report is of Castleman's disease presenting as a neck mass, an infrequent occurrence, with an analysis of management controversies and a review of the literature.
卡斯特leman病是一种罕见的良性淋巴组织疾病,通常发生于纵隔(70%),被认为是由未知来源的抗原性过度刺激引起的。根据两种不同的临床模式可发现两种组织学亚型,这具有临床和治疗意义。由于影像学检查未发现特异性特征,诊断通常仅在手术后通过组织学分析完成。手术切除对局限性形式既是诊断性的也是治愈性的,而多中心形式则需要额外的治疗。本报告介绍了以颈部肿块形式出现的卡斯特leman病,这种情况较为罕见,并分析了管理方面的争议以及对文献进行了综述。