Puech Philippe, Betrouni Nacim, Viard Romain, Villers Arnauld, Leroy Xavier, Lemaitre Laurent
Inserm, U703 of Lille, France.
Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:5567-70. doi: 10.1109/IEMBS.2007.4353608.
ProCAD is a computer assisted diagnosis (CAD) software dedicated to prostate DCE-MRI analysis.
In addition to standard visualization features, 2D and multislice 2D contouring tools based on a seeded growing region algorithm were included in the software. Tumor volume assessment and semiquantitative analysis of suspicious lesions can be performed. A 5-levels cancer suspicion score (ranging from "probably benign" to "Highly suspicious" is calculated on the basis of adjusted parameters extracted from the data of 121 suspicious benign or tumoral lesions.
Using a simple scoring algorithm based the median w.i and w.o values of TZK, TZB, PZK and PZB and designed to provide the highest sensitivity we had respective Se/Sp of 100/49% for peripheral zone cancers, and 100/40% for transition zone cancers characterization.
This software provides useful data for an unbiased an reproducible assessment of hypervascularized prostatic areas in routine practice.
ProCAD是一款专门用于前列腺动态对比增强磁共振成像（DCE-MRI）分析的计算机辅助诊断（CAD）软件。
除了标准的可视化功能外，该软件还包含基于种子生长区域算法的二维和多层二维轮廓工具。可以进行肿瘤体积评估和对可疑病变的半定量分析。根据从121个可疑良性或肿瘤性病变数据中提取的调整参数，计算出一个五级癌症怀疑评分（范围从“可能良性”到“高度可疑”）。
使用基于TZK、TZB、PZK和PZB的中位数w.i和w.o值的简单评分算法，并旨在提供最高灵敏度，对于外周带癌，我们分别有100/49%的灵敏度/特异度，对于移行带癌特征化有100/40%的灵敏度/特异度。
该软件为在常规实践中对前列腺高血运区域进行无偏倚且可重复的评估提供了有用数据。
