Vingård E, Alfredsson L, Goldie I, Hogstedt C
Department of Occupational Medicine, Karolinska Hospital, Stockholm, Sweden.
Int J Epidemiol. 1991 Dec;20(4):1025-31. doi: 10.1093/ije/20.4.1025.
A register-based cohort study was performed to investigate if men and women in certain occupations with high physical workload had increased risks of developing severe symptomatic osteoarthrosis of the hip and knee, resulting in hospital care. The study population consisted of 250,217 people from the 1980 census, in blue-collar occupations, who had reported the same occupation in the 1960 and 1970 censuses. The study population was followed for hospital care for osteoarthrosis of the hip and knee during 1981-1983 by linkage to the Swedish Hospital Discharge Register. Different blue-collar occupations were classified as high or low with regard to exposure to forces acting on the hip and knee and the frequencies of the outcomes were compared. Male farmers, construction workers, firefighters and some food processing workers had an excess risk of hospitalization due to osteoarthrosis of the hip. Male farmers, construction workers and firefighters also had increased risks of osteoarthrosis of the knee. Female mail carriers had an excess risk of osteoarthrosis of the hip, and female cleaners, of osteoarthrosis of the knee. The findings support the hypothesis that heavy physical work load contributes to osteoarthrosis of the hip and knee.
开展了一项基于登记资料的队列研究，以调查从事某些体力劳动强度大的职业的男性和女性患严重症状性髋部和膝部骨关节炎并需要住院治疗的风险是否增加。研究人群包括1980年人口普查中从事蓝领职业的250217人，他们在1960年和1970年人口普查中报告的职业相同。通过与瑞典医院出院登记册建立联系，对研究人群在1981 - 1983年期间髋部和膝部骨关节炎的住院治疗情况进行了随访。根据髋部和膝部所受作用力的暴露程度，将不同的蓝领职业分为高暴露组或低暴露组，并比较了不同组结局的发生频率。男性农民、建筑工人、消防员和一些食品加工工人因髋部骨关节炎住院的风险过高。男性农民、建筑工人和消防员患膝部骨关节炎的风险也增加。女性邮递员患髋部骨关节炎的风险过高，女性清洁工患膝部骨关节炎的风险过高。这些发现支持了重体力劳动会导致髋部和膝部骨关节炎这一假说。
