Misago N, Takahashi M, Kohda H
Department of Internal Medicine, Saga Medical School, Japan.
J Dermatol. 1991 Nov;18(11):649-53. doi: 10.1111/j.1346-8138.1991.tb03150.x.
A case of dysplastic nevi associated with malignant melanoma was reported. The case was characterized by unilateral distribution of dysplastic nevi. Multiple dysplastic nevi were observed only dorsally on the patient's left upper quadrant. To the best of our knowledge, the report of this form of dysplastic nevi is the first in Japan. In addition, dysplastic nevus cell nests were present in histologic contiguity with intraepidermal proliferation of melanoma in the radial growth phase. Histological evidence suggested that the melanoma in our case had probably been derived from the context of dysplastic nevus.
报告了1例发育异常痣伴发恶性黑色素瘤的病例。该病例的特征为发育异常痣呈单侧分布。仅在患者左上腹背部观察到多个发育异常痣。据我们所知,这种形式的发育异常痣在日本的报道尚属首次。此外,在组织学上,发育异常痣细胞巢与处于放射状生长期的黑色素瘤表皮内增殖相邻。组织学证据表明,我们病例中的黑色素瘤可能起源于发育异常痣背景。