Fried B, Peoples R C
Department of Biology, Lafayette College, Easton PA 18042, USA.
J Helminthol. 2008 Mar;82(1):95-6. doi: 10.1017/S0022149X0785824X. Epub 2007 Nov 16.
This study used Balb/c mice to examine the longevity of Echinostoma caproni. Five mice each exposed to 75 encysted metacercariae (cysts) were necropsied at 23 weeks postinfection (PI) (160 days PI). Two of the 5 were infected with a total of 33 worms; 23 in one mouse and 10 in the other. Body and organ area measurements showed that these worms were robust and normal in appearance. No signs of atrophy of any of the genital structures were observed. The mean +/- SE of eggs/uterus per worm (n = 10) was 243 +/- 6. This strain of mouse will be suitable to study the effect of long-term survival on the host-parasite relationship of E. caproni in Balb/c mice.
本研究使用Balb/c小鼠来检测卡氏棘口吸虫的寿命。每组5只小鼠，每只感染75个包囊后尾蚴（囊蚴），在感染后23周（感染后160天）进行尸检。5只小鼠中有2只共感染了33条虫；一只小鼠感染23条，另一只感染10条。身体和器官面积测量显示，这些虫外观健壮且正常。未观察到任何生殖结构萎缩的迹象。每条虫子宫内的平均卵数±标准误（n = 10）为243±6。该品系小鼠将适合用于研究长期存活对卡氏棘口吸虫在Balb/c小鼠中宿主-寄生虫关系的影响。
