病毒对自噬的逃避
Viral evasion of autophagy.
作者信息
Münz Christian
机构信息
Laboratory of Viral Immunobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
出版信息
Cell Host Microbe. 2007 Mar 15;1(1):9-11. doi: 10.1016/j.chom.2007.02.005.
PMID:18005677
Abstract
Restriction of both bacterial and viral pathogen growth by autophagy has been documented in vitro. In this issue of Cell Host & Microbe, Orvedahl et al. demonstrate for the first time that inhibition of autophagy by a viral gene product is essential for neurovirulence of herpesviruses.
摘要
自噬对细菌和病毒病原体生长的限制已在体外得到证实。在本期《细胞宿主与微生物》中，奥韦达尔等人首次证明，病毒基因产物对自噬的抑制作用对于疱疹病毒的神经毒性至关重要。
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