Münz Christian
Laboratory of Viral Immunobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
Cell Host Microbe. 2007 Mar 15;1(1):9-11. doi: 10.1016/j.chom.2007.02.005.
Restriction of both bacterial and viral pathogen growth by autophagy has been documented in vitro. In this issue of Cell Host & Microbe, Orvedahl et al. demonstrate for the first time that inhibition of autophagy by a viral gene product is essential for neurovirulence of herpesviruses.
自噬对细菌和病毒病原体生长的限制已在体外得到证实。在本期《细胞宿主与微生物》中，奥韦达尔等人首次证明，病毒基因产物对自噬的抑制作用对于疱疹病毒的神经毒性至关重要。
