Knobloch Karsten, Spies Marcus, Vogt Peter M, Phillips Rob
Int J Cardiol. 2009 Jan 24;131(3):413-5. doi: 10.1016/j.ijcard.2007.07.112. Epub 2007 Nov 14.
The relationship of non-invasive CW Doppler cardiac output (COUSCOM) and stroke volume (SVUSCOM) and calculated COSTRINGER and SVSTRINGER based on the Stringer calculations in healthy athletes is unknown.
20 athletes (19.9+/-11 years) underwent a standardized stepwise treadmill test including breath-by-breath spirometry, and non-invasive SVUSCOM and COUSCOM. Stringer formula a-vDO2=5.721+(0.1047%VO2max) and CO=VO2/C(a-vDO2) (direct Fick method) were applied.
Total values of COSTRINGER vs. COUSCOM and SVSTRINGER vs. SVUSCOM showed high correlation (r=0.879 and r=0.813, p<0.01). Mean differences between total measures of COSTRINGER vs. COUSCOM were 0.4+/-4.1 l/min and SVSTRINGER vs. SVUSCOM -9.9+/-19.9 cm3. Mean % errors were COSTRINGER vs. COUSCOM -31+/-66% and SVSTRINGER vs. SVUSCOM -39+/-58% respectively. Regression modelling determined COSTRINGER=1.58CO-4.02 l/min, and SVSTRINGER=1.45SV-35.60 cm3. SVSTRINGER vs. SVUSCOM correlated best at peak exercise (r=0.997), followed by r=0.668 at recovery3 min and 0.585 at recovery1 min. COSTRINGER vs. COUSCOM correlated best at recovery3 min (r=0.611), followed by recovery1 min (r=0.556) and moderately at peak exercise (r=0.447). At rest, both COSTRINGER and SVSTRINGER were not correlated with COUSCOM and SVUSCOM (r=0.276 and r=0.130, respectively).
Calculated SVSTRINGER and COSTRINGER are applicable at peak exercise and during recovery compared to CW Doppler SVUSCOM and COUSCOM. However certain limitations are evident regarding calculated COSTRINGER at peak exercise and at rest in comparison to CW Doppler measurements.
在健康运动员中，无创连续波多普勒心输出量（COUSCOM）和每搏输出量（SVUSCOM）与基于斯特林格计算得出的计算心输出量（COSTRINGER）和计算每搏输出量（SVSTRINGER）之间的关系尚不清楚。
20名运动员（19.9±1.1岁）接受了标准化的逐步跑步机测试，包括逐次呼吸肺量计检查以及无创SVUSCOM和COUSCOM测量。应用了斯特林格公式a-vDO2 = 5.721 +（0.1047×最大摄氧量%）以及心输出量=最大摄氧量/C（a-vDO2）（直接菲克法）。
COSTRINGER与COUSCOM的总值以及SVSTRINGER与SVUSCOM的总值显示出高度相关性（r = 0.879和r = 0.813，p<0.01）。COSTRINGER与COUSCOM的总测量值之间的平均差异为0.4±4.1升/分钟，SVSTRINGER与SVUSCOM的平均差异为-9.9±19.9立方厘米。平均百分比误差分别为COSTRINGER与COUSCOM -31±66%以及SVSTRINGER与SVUSCOM -39±58%。回归模型确定COSTRINGER = 1.58×心输出量-4.02升/分钟，以及SVSTRINGER = 1.45×每搏输出量-35.60立方厘米。SVSTRINGER与SVUSCOM在运动峰值时相关性最佳（r = 0.997），其次在恢复3分钟时为r = 0.668，在恢复1分钟时为0.585。COSTRINGER与COUSCOM在恢复3分钟时相关性最佳（r = 0.611），其次在恢复1分钟时为r = 0.556，在运动峰值时为中等相关性（r = 0.447）。在静息状态下，COSTRINGER和SVSTRINGER与COUSCOM和SVUSCOM均无相关性（分别为r = 0.276和r = 0.130）。
与连续波多普勒SVUSCOM和COUSCOM相比，计算得出的SVSTRINGER和COSTRINGER在运动峰值和恢复期间适用。然而，与连续波多普勒测量相比，计算得出的COSTRINGER在运动峰值和静息状态下存在明显局限性。
