来自小花异檐花的细胞毒性降二萜内酯。

Cytotoxic norditerpene lactones from Ileostylus micranthus.

作者信息

Bloor S J, Molloy B P

机构信息

DSIR Chemistry, Petone, New Zealand.

出版信息

J Nat Prod. 1991 Sep-Oct;54(5):1326-30. doi: 10.1021/np50077a015.

DOI:10.1021/np50077a015

PMID:1800635

Abstract

Three new compounds 2-4 and two known compounds 1 and 5 have been isolated from the cytotoxic fraction of an extract from a New Zealand mistletoe, Ileostylus micranthus. Compounds 1-5 are shown to be norditerpene lactones and have strong cytotoxicity. The compounds are proposed to have been assimilated by the mistletoe from the host tree, Podocarpus totara.

摘要

从新西兰寄生植物小花艾氏寄生（Ileostylus micranthus）提取物的细胞毒性组分中分离出了三种新化合物2 - 4以及两种已知化合物1和5。化合物1 - 5被证明是降二萜内酯，并且具有很强的细胞毒性。这些化合物被认为是寄生植物从小叶罗汉松宿主树中吸收而来的。