Elwes R D, Dunn G, Binnie C D, Polkey C E
Institute of Psychiatry, De Crespigny Park, London, UK.
J Neurol Neurosurg Psychiatry. 1991 Nov;54(11):949-52. doi: 10.1136/jnnp.54.11.949.
The long term outcome has been assessed in a consecutive series of 102 cases undergoing resective temporal lobe surgery because of medically intractable epilepsy. Patients were followed prospectively for a median of 61 months. Actuarial statistics were used to measure the temporal patterns of remission and stability of outcome over prolonged periods of observation. The probability of achieving one year remission was 57% by one year, 70% by two years, and 77% by seven years. Once a patient was in one year remission the probability of remaining seizure free was 90%. This rose to 94% after two consecutive years of being seizure free. The majority of patients who remit following surgery have done so by two years of follow up. Outcome at the end of the second post operative year is a good predictor of long term prognosis.
对因药物难治性癫痫接受颞叶切除术的102例连续病例的长期结果进行了评估。对患者进行前瞻性随访，中位随访时间为61个月。采用精算统计方法来衡量长期观察期间缓解和结果稳定性的时间模式。一年缓解的概率在1年时为57%，2年时为70%，7年时为77%。一旦患者实现一年缓解，无癫痫发作的概率为90%。连续两年无癫痫发作后，这一概率升至94%。大多数术后缓解的患者在随访两年时就已缓解。术后第二年结束时的结果是长期预后的良好预测指标。
