Kitchen N D, Cook M J, Shorvon S D, Fish D R, Thomas D G
Department of Neurological Surgery, Institute of Neurology, London, UK.
J Neurol Neurosurg Psychiatry. 1994 Oct;57(10):1221-7. doi: 10.1136/jnnp.57.10.1221.
Studies on surgery for temporal lobe epilepsy are hampered by lack of information about the actual surgery that has taken place. A method is described for accurately measuring the volumes of resection by MRI after surgery. Ten cases of surgically treated temporal lobe epilepsy (nine non-tailored resections, one selective amygdalohippocampectomy) are presented to show the technique. Indices of extent of resection in both the mesiobasal and lateral temporal lobe compartments have been measured, compared, and evaluated. By comparison with identical preoperative volumetric MRI the hippocampal resections have been correlated with the demonstrated hippocampal volume loss, thought to be of relevance in the aetiology of temporal lobe epilepsy. Detailed postoperative audit in this manner is vital in providing a rational basis for follow up studies of outcome.
由于缺乏关于实际进行的手术的信息，颞叶癫痫手术的研究受到阻碍。本文描述了一种通过术后MRI精确测量切除体积的方法。介绍了10例接受手术治疗的颞叶癫痫病例（9例非定制切除术，1例选择性杏仁核海马切除术）以展示该技术。测量、比较并评估了颞叶内侧基底和外侧部分的切除范围指标。通过与术前相同的容积MRI进行比较，海马切除术与已证实的海马体积缩小相关，这被认为与颞叶癫痫的病因有关。以这种方式进行详细的术后审核对于为结果的随访研究提供合理依据至关重要。
