Studies on the synthesis and reactivity of novel benzofuran-2-yl-[3-methyl-3-phenylcyclobutyl] methanones and their antimicrobial activity.
作者信息
Koca Murat, Ahmedzade Misir, Cukurovali Alaaddin, Kazaz Cavit
机构信息
Firat University, Faculty of Arts and Sciences, Chemistry Department, 23119 Elazig, Turkey.
出版信息
Molecules. 2005 Aug 31;10(7):747-54. doi: 10.3390/10070747.
Abstract
Preparation in excellent yields of cyclobutyl benzofuran-2-yl- and naphthofuran- 2-yl-ketones, the corresponding ketoximes and thiosemicarbazones, ether derivatives of the ketoximes and thiazoles derived from the thiosemicarbazones are described. Two of the synthesized compounds have been tested against eight different microorganisms and found to be active against some of the species studied.
摘要
相似文献
1
Studies on the synthesis and reactivity of novel benzofuran-2-yl-[3-methyl-3-phenylcyclobutyl] methanones and their antimicrobial activity.
Molecules. 2005 Aug 31;10(7):747-54. doi: 10.3390/10070747.
2
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives.苯并呋喃一些新型衍生物的合成与抗菌活性：第1部分。(苯并呋喃-2-基)(3-苯基-3-甲基环丁基)酮肟衍生物的合成与抗菌活性
Eur J Med Chem. 2005 Dec;40(12):1351-8. doi: 10.1016/j.ejmech.2005.07.004. Epub 2005 Aug 29.
3
Synthesis, reactivity and biological activity of novel bisbenzofuran-2-yl-methanone derivatives.新型双苯并呋喃-2-基-甲酮衍生物的合成、反应活性及生物活性
Molecules. 2005 Nov 30;10(11):1399-408. doi: 10.3390/10111399.
4
Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes.某些芳基[3-(咪唑-1-基/三唑-1-基甲基)苯并呋喃-2-基]酮肟的合成及其抗真菌活性
Eur J Med Chem. 2006 May;41(5):651-6. doi: 10.1016/j.ejmech.2005.12.013. Epub 2006 Mar 22.
5
NEW HETEROCYCLIC OXIME ETHERS OF 1-(BENZOFURAN-2-YL)ETHAN- 1-ONE AND THEIR ANTIMICROBIAL ACTIVITY.1-（苯并呋喃-2-基）乙-1-酮的新型杂环肟醚及其抗菌活性
Acta Pol Pharm. 2015 Mar-Apr;72(2):289-95.
6
Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes.一些芳基（苯并呋喃-2-基）酮肟的合成及其抗真菌活性
Farmaco. 2002 Jul;57(7):609-12. doi: 10.1016/s0014-827x(02)01257-0.
7
Synthesis of some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives and their antimicrobial activity and toxicity.一些2-[(苯并唑-2-基)硫代乙酰氨基]噻唑衍生物的合成及其抗菌活性和毒性
Eur J Med Chem. 2004 Mar;39(3):267-72. doi: 10.1016/j.ejmech.2003.11.001.
8
Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents.新型（E）-1-（4-甲基-2-（烷基氨基）噻唑-5-基）-3-芳基丙烯-1-酮类化合物作为有效的抗菌剂。
Bioorg Med Chem. 2011 Dec 15;19(24):7349-56. doi: 10.1016/j.bmc.2011.10.059. Epub 2011 Oct 25.
9
10
Synthesis and characterization of selected methyl 5-methoxy-2-methyl-1-benzofuran-3-carboxylate derivatives with potential antimicrobial activity.
Acta Pol Pharm. 2012 Nov-Dec;69(6):1055-65.
本文引用的文献
1
Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1.新型苯并呋喃类化合物作为靶向真菌N-肉豆蔻酰转移酶的新型抗真菌剂的设计与合成。第1部分。
Bioorg Med Chem Lett. 2001 Jul 23;11(14):1833-7. doi: 10.1016/s0960-894x(01)00319-5.
2
The conformation and activity relationship of benzofuran derivatives as angiotensin II receptor antagonists.
Bioorg Med Chem. 1997 Feb;5(2):445-59. doi: 10.1016/s0968-0896(96)00244-1.
3
Substituted 1-[benzofuran-2-yl)-phenylmethyl]-imidazoles as potent inhibitors of aromatase in vitro and in female rats in vivo.取代的1-[(苯并呋喃-2-基)-苯基甲基]-咪唑类化合物作为体外和雌性大鼠体内强效芳香化酶抑制剂
J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):675-6. doi: 10.1016/0960-0760(93)90279-6.
4
Structure and function of DNA photolyase.DNA光解酶的结构与功能。
Biochemistry. 1994 Jan 11;33(1):2-9. doi: 10.1021/bi00167a001.
Zotero 插件