Abdullah Z, Tahir N Mohd, Abas M R, Aiyub Z, Low B K
Department of Chemistry, Faculty of Science, Univ. of Malaya, 50603, Kuala Lumpur, Malaysia.
Molecules. 2004 Jun 30;9(7):520-6. doi: 10.3390/90700520.
The reactions of 2-chloropyrimidine with methylamine, ethylamine and piperidine gave the corresponding 2-N-methylamino-, 2-N-ethylamino- and 2N- piperidinopyrimidines, respectively. The fluorescence properties of these alkylamino derivatives in chloroform, ethyl acetate, carbon tetrachloride, acetone, ether, ethanol and methanol were studied. All the alkylamino derivatives showed the highest fluorescence intensity in polar protic solvents; thus 2-N-methylaminopyrimidine (highest fluorescence intensity at 377 nm when excited at 282 nm) and 2-N-ethylaminopyrimidine (highest fluorescence intensity at 375 nm, when excited at 286 nm) showed the highest fluorescence in methanol. In ethanol, 2-N-piperidinopyrimidine showed a fluorescence peak at 403 nm when excited at 360 nm and in chloroform it fluoresced at 392 nm when excited at 356 nm.
2-氯嘧啶与甲胺、乙胺和哌啶反应，分别生成相应的2-N-甲基氨基-、2-N-乙基氨基-和2-N-哌啶基嘧啶。研究了这些烷基氨基衍生物在氯仿、乙酸乙酯、四氯化碳、丙酮、乙醚、乙醇和甲醇中的荧光性质。所有烷基氨基衍生物在极性质子溶剂中显示出最高的荧光强度；因此，2-N-甲基氨基嘧啶（在282nm激发时，377nm处荧光强度最高）和2-N-乙基氨基嘧啶（在286nm激发时，375nm处荧光强度最高）在甲醇中显示出最高荧光。在乙醇中，2-N-哌啶基嘧啶在360nm激发时，在403nm处有一个荧光峰，在氯仿中，在356nm激发时，在392nm处发出荧光。
