Ladero Quesada J M, Amarillas Sánchez L, Furió Bacete V, Laredo Velasco L
Departamento de Medicina, Hospital Universitario de San Carlos, Madrid.
Rev Clin Esp. 1991 Oct;189(5):221-3.
A patient who had been successfully treated of Hodgkin's disease (nodular sclerotic type) with mediastinal radiotherapy and polychemotherapy, suffered an acute pericarditis immediately after radiotherapy and a complete atrial-ventricular block 14 years later. Five years later she presented refractory hemorrhagic peritonitis. Necropsy study showed a peritoneal mesothelioma (in non radiated area) and diffuse subpericardial fibrosis. Complete A-V block is a very rare late complication of mediastinal radiotherapy and mesotheliomas (almost exclusively in irradiated areas), also. We have not found any reports on other cases of peritoneal mesotheliomas not attributable to radiotherapy as second neoplasia in Hodgkin's disease.
一名曾接受纵隔放疗和多药化疗成功治疗霍奇金病（结节硬化型）的患者，放疗后立即发生急性心包炎，14年后出现完全性房室传导阻滞。5年后，她出现难治性出血性腹膜炎。尸检研究显示腹膜间皮瘤（在未受辐射区域）和弥漫性心包下纤维化。完全性房室传导阻滞是纵隔放疗非常罕见的晚期并发症，间皮瘤（几乎仅在受辐射区域）也是如此。我们未发现任何关于霍奇金病中作为第二肿瘤的、非放疗所致腹膜间皮瘤其他病例的报道。
