Leong Fah Che, McLennan Mary T
Department of Obstetrics, Gynecology and Women's Health, Division of Urogynecology and Reconstructive Pelvic Surgery, Saint Louis University School of Medicine, USA.
Mo Med. 2007 Sep-Oct;104(5):435-9.
The prevalence of overactive bladder (OAB) in the United States ranges from 10% - 30%. The mainstay of treatment is anticholinergic medication. All agents have significant side effects and at least 30% of patients fail to respond. This paper reviews neuromodulation which involves the use of electrical stimulation of either the sacral or peripheral nerves to modify the behavior of the bladder. It is an option for patients who either cannot tolerate medications or fail therapy.
在美国,膀胱过度活动症(OAB)的患病率在10%至30%之间。治疗的主要方法是抗胆碱能药物。所有药物都有显著的副作用,至少30%的患者对治疗无反应。本文综述了神经调节,即通过对骶神经或周围神经进行电刺激来改变膀胱的行为。对于那些无法耐受药物治疗或治疗失败的患者来说,这是一种选择。