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模拟小血管中成核位点处气泡的脱离与传输。

Modeling the detachment and transport of bubbles from nucleation sites in small vessels.

作者信息

Chappell Michael A, Uzel Sébastien, Payne Stephen J

机构信息

Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK.

出版信息

IEEE Trans Biomed Eng. 2007 Nov;54(11):2106-8. doi: 10.1109/TBME.2007.895113.

Abstract

Decompression sickness is known to be due to the formation of bubbles in the body as a result of decompression. It is likely that these bubbles form from pre-existing nuclei, which, for bubbles in the bloodstream, are thought to be housed within blood vessel walls. Gas pockets emerging from these sites will be subject to forces due to blood flow, a portion of the gas eventually being swept away to form a free bubble in the bloodstream. These continue to grow and may grow to similar dimensions to the vessel, developing into elongated "gas plugs," potentially occluding the flow. In this correspondence, we derive a simple model to investigate whether this vessel occlusion is a serious concern.

摘要

减压病被认为是减压导致身体内形成气泡所致。这些气泡很可能由预先存在的核形成,对于血液中的气泡,这些核被认为存在于血管壁内。从这些部位出现的气穴会受到血流的作用力,一部分气体最终会被冲走,在血液中形成游离气泡。这些气泡会持续生长,可能会长到与血管相似的尺寸,发展成细长的“气栓”,有可能阻塞血流。在本通信中,我们推导了一个简单模型来研究这种血管阻塞是否是一个严重问题。

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