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灾难事件与心源性猝死风险:华盛顿州的一项调查

Disaster events and the risk of sudden cardiac death: a Washington State investigation.

作者信息

Gold Laura S, Kane Leslee B, Sotoodehnia Nona, Rea Thomas

机构信息

University of Washington School of Public Health and Community Medicine, Department of Epidemiology, Seattle, Washington, USA.

出版信息

Prehosp Disaster Med. 2007 Jul-Aug;22(4):313-7. doi: 10.1017/s1049023x00004921.

Abstract

BACKGROUND

Psychological distress following disaster events may increase the risk of sudden cardiac death. In 2001, the Nisqually earthquake and the 11 September terrorist attacks profoundly affected Washington state residents.

HYPOTHESIS

This research investigated the theory that the incidence of sudden cardiac death would increase following these disaster events.

METHODS

Death certificates were abstracted using a uniform case definition to determine the number of sudden cardiac deaths for the 48-hour and one-week periods following the two disaster events. Sudden cardiac deaths from the corresponding 48-hour and one-week periods in the three weeks before the events, and the analogous periods in 1999 and 2000 were designated as control times. Using t-tests, the number of sudden cardiac deaths for the periods following the disaster events was compared to those of the control periods.

RESULTS

In total, 32 sudden cardiac deaths occurred in the four counties affected by the Nisqually earthquake during the 48 hours after the event, compared to an average of 22 +/- 3.5 (standard deviation) in the same counties during the control periods (p = 0.02). No difference was observed for the one-week period (94 compared to 79.2 +/- 12.4, p = 0.28). No difference was observed in the number of sudden cardiac deaths in the 48-hours or one-week following the terrorist attacks compared to control periods.

CONCLUSIONS

A local disaster caused by a naturally occurring hazard, but not a geographically remote human disaster, was associated with an increased risk of sudden cardiac death. A better understanding of the underlying mechanisms may have implications for prevention of sudden cardiac death.

摘要

背景

灾难事件后的心理困扰可能会增加心源性猝死的风险。2001年,尼斯夸利地震和9月11日恐怖袭击对华盛顿州居民产生了深远影响。

假设

本研究调查了灾难事件后心源性猝死发生率会增加这一理论。

方法

使用统一的病例定义提取死亡证明,以确定这两次灾难事件后48小时和一周内的心源性猝死人数。将事件发生前三周相应的48小时和一周内的心源性猝死人数,以及1999年和2000年的类似时间段指定为对照时间。使用t检验,将灾难事件后各时间段的心源性猝死人数与对照时间段的人数进行比较。

结果

在尼斯夸利地震影响的四个县,事件发生后的48小时内共发生了32例心源性猝死,而对照时间段内这些县的心源性猝死平均人数为22±3.5(标准差)(p = 0.02)。在一周时间段内未观察到差异(94例与79.2±12.4例相比,p = 0.28)。与对照时间段相比,恐怖袭击后48小时或一周内的心源性猝死人数未观察到差异。

结论

由自然危害引起的局部灾难,而非地理上遥远的人为灾难,与心源性猝死风险增加有关。更好地理解潜在机制可能对预防心源性猝死具有重要意义。

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