Rácil Z, Kocmanová I, Wagnerová B, Lengerová M, Mayer J
Interní hematoonkologická klinika Lékarské fakulty MU a FN Brno.
Vnitr Lek. 2007 Sep;53(9):990-9.
Invasive fungal infections have become one of the major causes of morbidity and mortality in hematooncological patients over the past 2 decades. Even there is an increasing incidence of invasive fungal infections caused by rare filamentous fungi, the majority of infections are caused by Candida sp. and especially Aspergillus sp. Early diagnosis and prompt initiation of antifungal treatment are leading factors influencing prognosis of patients with invasive fungal infection. Important advances in the field of early diagnosis of invasive fungal infections have been realized over the last years. Beside of new radiological methods the major progress has been done in serological methods. In this paperwe review the most important of these serological methods and their position in routine clinical practice.
在过去20年中，侵袭性真菌感染已成为血液肿瘤患者发病和死亡的主要原因之一。尽管由罕见丝状真菌引起的侵袭性真菌感染发病率在上升，但大多数感染是由念珠菌属，尤其是曲霉属引起的。早期诊断和及时开始抗真菌治疗是影响侵袭性真菌感染患者预后的主要因素。在侵袭性真菌感染的早期诊断领域，过去几年已取得了重要进展。除了新的放射学方法外，血清学方法也取得了重大进展。在本文中，我们综述了这些血清学方法中最重要的方法及其在常规临床实践中的地位。
