Floman Y
Spinal Surgery Unit, Hadassah University Hospital, Ein-Kerem, Jerusalem, Israel.
J Spinal Disord. 1991 Sep;4(3):366-8. doi: 10.1097/00002517-199109000-00015.
Congenital scoliosis, which is caused by isolated anomalies (as opposed to multiple spinal anomalies and myelomeningocoele), is usually a nonfamilial condition. In rare instances, however, a congenital spine deformity is genetically determined. We herein report a brother and sister with a nearly identical "mirror image" congenital lumbar scoliosis. We conclude that the presence of a congenital spine deformity necessitates the screening of other siblings for a similar anomaly.
先天性脊柱侧弯由孤立性异常(与多发性脊柱异常和脊髓脊膜膨出相对)引起,通常不属于家族性疾病。然而,在罕见情况下,先天性脊柱畸形是由基因决定的。我们在此报告一对兄妹患有几乎相同的“镜像”先天性腰椎侧弯。我们得出结论,对于存在先天性脊柱畸形的情况,有必要对其他兄弟姐妹进行类似异常的筛查。