Herlitz Johan, Svensson Leif, Engdahl Johan, Gelberg Jan, Silfverstolpe Johan, Wisten Aase, Angquist Karl-Axel, Holmberg Stig
Department of Metabolism and Cardiovascular Research, Institute of Internal Medicine, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.
Am J Emerg Med. 2007 Nov;25(9):1025-31. doi: 10.1016/j.ajem.2007.03.008.
The objective of this study was to describe patients who experienced an out-of-hospital cardiac arrest (OHCA) by age group.
All patients who suffered from an OHCA between 1990 and 2005 and are included in the Swedish Cardiac Arrest Registry (n = 40,503) were classified into the following age groups: neonates, younger than 1 year; young children, between 1 and 4 years; older children, between 5 and 12 years; adolescents, between 13 and 17 years; young adults, between 18 and 35 years; adults not retired, between 36 and 64 years; adults retired, between 65 and 79 years; and older adults, 80 years or older.
Ventricular fibrillation was lowest in young children (3%) and highest in adults (35%). Survival to 1 month was lowest in neonates (2.6%) and highest in older children (7.8%). Children (<18 years), young adults (18-35 years), and adults (>35 years) survived to 1 month 24.5%, 21.2%, and 13.6% of cases, respectively (P = .0003 for trend) when found in a shockable rhythm. The corresponding figures for nonshockable rhythms were 3.8%, 3.2%, and 1.6%, respectively (P < .0001 for trend).
There is a large variability in characteristics and outcome among patients in various age groups who experienced an OHCA. Among the large age groups, there was a successive decline in survival with increasing age in shockable and nonshockable rhythms.
本研究的目的是按年龄组描述经历院外心脏骤停(OHCA)的患者。
1990年至2005年间发生OHCA并纳入瑞典心脏骤停登记处的所有患者(n = 40,503)被分为以下年龄组:新生儿,小于1岁;幼儿,1至4岁;大龄儿童,5至12岁;青少年,13至17岁;青年成人,18至35岁;未退休成人,36至64岁;退休成人,65至79岁;以及老年人,80岁及以上。
室颤在幼儿中最低(3%),在成人中最高(35%)。1个月生存率在新生儿中最低(2.6%),在大龄儿童中最高(7.8%)。儿童(<18岁)、青年成人(18 - 35岁)和成人(>35岁)在可电击心律下1个月生存率分别为病例数的24.5%、21.2%和13.6%(趋势检验P = 0.0003)。不可电击心律的相应数字分别为3.8%、3.2%和1.6%(趋势检验P < 0.0001)。
经历OHCA的不同年龄组患者在特征和结局方面存在很大差异。在较大年龄组中,可电击和不可电击心律下的生存率均随年龄增长而连续下降。