Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Digital Health, Samsung Advanced Institute for Health Science & Technology (SAIHST), Sungkyunkwan University, Seoul, Korea.
J Korean Med Sci. 2022 Nov 14;37(44):e317. doi: 10.3346/jkms.2022.37.e317.
This study reports trends in pediatric out-of-hospital cardiac arrest (OHCA) and factors affecting clinical outcomes by age group.
We identified 4,561 OHCA patients younger than 18 years between January 2009 and December 2018 in the Korean OHCA Registry. The patients were divided into four groups: group 1 (1 year or younger), group 2 (1 to 5 years), group 3 (6 to 12 years), and group 4 (13 to 17 years). The primary outcome was survival to hospital discharge, and the secondary outcomes were return of spontaneous circulation (ROSC) at the emergency department (ED) and good neurological status at discharge. Multivariate logistic analyses were performed.
The incidence rate of pediatric OHCA in group 1 increased from 45.57 to 60.89 per 100,000 person-years, while that of the overall population decreased over the 10 years. The rates of ROSC at the ED, survival to hospital discharge, and good neurologic outcome were highest in group 4 (37.9%, 9.7%, 4.9%, respectively) and lowest in group 1 (28.3%, 7.1%, 3.2%). The positive factors for survival to discharge were event location of a public/commercial building or place of recreation, type of first responder, prehospital delivery of automated external defibrillator shock, initial shockable rhythm at the ED. The factors affecting survival outcomes differed by age group.
This study reports comprehensive trends in pediatric OHCA in the Republic of Korea. Our findings imply that preventive methods for the targeted population should be customized by age group.
本研究报告了儿科院外心脏骤停(OHCA)的趋势,并按年龄组分析了影响临床结局的因素。
我们在韩国 OHCA 注册中心确定了 2009 年 1 月至 2018 年 12 月期间 4561 名年龄小于 18 岁的 OHCA 患者。将患者分为四组:组 1(1 岁或更小)、组 2(1 至 5 岁)、组 3(6 至 12 岁)和组 4(13 至 17 岁)。主要结局是出院时存活,次要结局是急诊科(ED)恢复自主循环(ROSC)和出院时良好的神经状态。进行多变量逻辑分析。
组 1 的儿科 OHCA 发生率从每 100,000 人年的 45.57 增加到 60.89,而在这 10 年中,总人口的发生率却下降了。ED 的 ROSC 率、出院存活率和良好神经功能结局率最高的是组 4(分别为 37.9%、9.7%和 4.9%),最低的是组 1(分别为 28.3%、7.1%和 3.2%)。出院存活率的阳性因素包括公共/商业建筑或娱乐场所的事件位置、第一响应者类型、院前自动体外除颤器除颤电击、ED 初始可电击节律。各年龄组的生存结局影响因素不同。
本研究报告了韩国儿科 OHCA 的全面趋势。我们的研究结果表明,应根据年龄组定制针对特定人群的预防方法。