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腹壁硬纤维瘤的最新进展。

Updates on abdominal desmoid tumors.

作者信息

Rampone Bernardino, Pedrazzani Corrado, Marrelli Daniele, Pinto Enrico, Roviello Franco

机构信息

Department of General Surgery and Surgical Oncology, Unit of Surgical Oncology, University of Siena, Policlinico Le Scotte, viale Bracci, 1, 53100, Siena, Italy.

出版信息

World J Gastroenterol. 2007 Dec 7;13(45):5985-8. doi: 10.3748/wjg.v13.45.5985.

Abstract

Desmoid tumor is a monoclonal, fibroblastic proliferation arising in musculoaponeurotic structures. This connective tissue hyperplasia infiltrates locally, recurs frequently after resection but does not metastasize. Abdominal desmoid occurs sporadically, in association with some familial syndromes and often represents a clinical dilemma for surgeons. The enigmatic biology and anatomical location of abdominal desmoids make treatment recommendations difficult. This distinct pathological entity is reviewed with a specific focus on aetiology and management.

摘要

硬纤维瘤是一种起源于肌筋膜结构的单克隆性成纤维细胞增殖。这种结缔组织增生呈局部浸润性生长,切除后常复发,但不发生转移。腹部硬纤维瘤可散发,也可与某些家族综合征相关,常给外科医生带来临床难题。腹部硬纤维瘤神秘的生物学特性和解剖位置使得治疗建议难以确定。本文对这一独特的病理实体进行综述,特别关注其病因和治疗。

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