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非炎性分支及视网膜中央动脉阻塞中的全身性疾病——416例患者的概述

Systemic diseases in non-inflammatory branch and central retinal artery occlusion--an overview of 416 patients.

作者信息

Schmidt Dieter, Hetzel A, Geibel-Zehender A, Schulte-Mönting J

机构信息

University Eye Hospital, Killianstr. 5, 79106 Freiburg, Germany.

出版信息

Eur J Med Res. 2007 Dec 14;12(12):595-603.

Abstract

BACKGROUND

To determine the frequency of essential cardiovascular risk factors in different vascular ocular diseases. -

METHODS

We compiled cardiovascular risk factor findings (RFs) from 416 patients with non-inflammatory ocular vascular occlusions in a retrospective study: 134 patients with BRAO, 253 patients with CRAO, and 29 patients with hemi-CRAO. 274 (65.9 %) male and 142 (34.1 %) female patients were examined. Mean age of all patients was 66 years (range: 18-90). The right eye was involved in 221 (53.1 %), left eye in 193 (46.4 %), and both eyes in 2 patients (0.5 %). -

RESULTS

Cardiovascular risk factors (RFs) were found in 243 patients. Three hundred and eight (308) out of 406 patients (75.9 %) presented with arterial hypertension. Hypertension was present in 96 patients with BRAO (73.8 %), in 197 patients with CRAO (79.8 %), and in 15 patients with hemi-CRAO (78.9 %). - RFs such as arterial hypertension, carotid artery diseases, diabetes mellitus, hyperlipidemia, hyperuricemia, and chronic smoking did not differ statistically between patients with BRAO, CRAO or hemi--CRAO. But visible emboli in retinal arteries were observed in patients with BRAO (47 %,), or hemi-CRAO (41.4 %), much more often than in patients with CRAO (11.1 %). -

CONCLUSIONS

No statistical differences between the RFs of patients with BRAO, CRAO, or hemi-CRAO were noted. We maintain that every patient with retinal arterial obstruction should undergo extensive examination of essential RFs.

摘要

背景

确定不同血管性眼病中主要心血管危险因素的频率。

方法

在一项回顾性研究中,我们汇总了416例非炎性眼部血管阻塞患者的心血管危险因素(RFs)结果:134例分支视网膜动脉阻塞(BRAO)患者、253例视网膜中央动脉阻塞(CRAO)患者和29例半侧视网膜中央动脉阻塞(hemi-CRAO)患者。共检查了274例(65.9%)男性和142例(34.1%)女性患者。所有患者的平均年龄为66岁(范围:18 - 90岁)。右眼受累221例(53.1%),左眼受累193例(46.4%),双眼受累2例(0.5%)。

结果

243例患者发现有心血管危险因素(RFs)。406例患者中有308例(75.9%)患有动脉高血压。BRAO患者中有96例(73.8%)患有高血压,CRAO患者中有197例(79.8%)患有高血压,hemi-CRAO患者中有15例(78.9%)患有高血压。BRAO、CRAO或hemi-CRAO患者的动脉高血压、颈动脉疾病、糖尿病、高脂血症、高尿酸血症和长期吸烟等RFs在统计学上无差异。但BRAO患者(47%)或hemi-CRAO患者(41.4%)视网膜动脉中可见栓子的情况比CRAO患者(11.1%)更常见。

结论

BRAO、CRAO或hemi-CRAO患者的RFs之间未发现统计学差异。我们认为,每例视网膜动脉阻塞患者都应接受主要RFs的全面检查。

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