Karakaya Osman, Barutcu Irfan, Kaya Dayimi, Esen Ali Metin, Saglam Mustafa, Melek Mehmet, Onrat Ersel, Turkmen Muhsin, Esen Ozlem Batukan, Kaymaz Cihangir
Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul and Afyon, Turkey.
Angiology. 2007 Oct-Nov;58(5):620-4. doi: 10.1177/0003319706294555.
Acute cigarette smoking enhances adrenergic activity and thus may be associated with hemodynamic changes in the cardiovascular system. In this study, the acute effect of cigarette smoking on heart rate variability (HRV) was studied. Fifteen subjects were included in the study. Time domain (the mean R-R interval, the standard deviation of R-R interval, and the root mean square of successive R-R interval differences) and frequency domain (high-frequency, low-frequency ratio, and low-frequency/high-frequency ratio) parameters of HRV were obtained from all participants for each 5-minute segment: 5 minutes before and 5, 10, 15, 20, 25, and 30 minutes after smoking a cigarette. The mean R-R interval, the standard deviation of R-R interval, and the root mean square of successive R-R interval differences significantly decreased within the first 5-minute period compared with baseline, and then the standard deviation of R-R interval increased within the 20- to 30-minute period. The low-frequency high-frequency ratio significantly decreased within the first 5 minutes after smoking and then remained unchanged throughout the study period. Similarly, low-frequency and high-frequency power increased within the first 5 minutes compared with baseline. Acute cigarette smoking alters HRV parameters, particularly within the first 5 to 10 minutes after smoking.
急性吸烟会增强肾上腺素能活性，因此可能与心血管系统的血流动力学变化有关。在本研究中，研究了吸烟对心率变异性（HRV）的急性影响。15名受试者纳入研究。从所有参与者中获取每个5分钟时间段（吸烟前5分钟以及吸烟后5、10、15、20、25和30分钟）HRV的时域参数（平均R-R间期、R-R间期标准差和连续R-R间期差值的均方根）和频域参数（高频、低频比值和低频/高频比值）。与基线相比，平均R-R间期、R-R间期标准差和连续R-R间期差值的均方根在最初5分钟内显著降低，然后R-R间期标准差在20至30分钟内增加。低频高频比值在吸烟后最初5分钟内显著降低，然后在整个研究期间保持不变。同样，与基线相比，低频和高频功率在最初5分钟内增加。急性吸烟会改变HRV参数，尤其是在吸烟后最初5至10分钟内。
