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Demonstration of a core in poliovirus particles by electron microscopy.

作者信息

Boublik M, Drzeniek R

出版信息

J Gen Virol. 1976 Jun;31(3):447-9. doi: 10.1099/0022-1317-31-3-447.

DOI:10.1099/0022-1317-31-3-447
PMID:180251
Abstract

Electron microscopic examination of poliovirus in CsCl-solutions without conventional staining with phosphotungstic acid or uranyl acetate revealed the existence of cores inside poliovirus particles. Empty capsids could not be visualized by this technique. Evidently, CsCl can enhance the contrast of the virus particle to an extent sufficient for the study of poliovirus particles by electron microscopy under conditions in which they exhibit specific properties.

摘要

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