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通过电子显微镜观察脊髓灰质炎病毒颗粒的结构亚基。

Structural subunits of poliovirus particles by electron microscopy.

作者信息

Boublik M, Drzeniek R

出版信息

J Gen Virol. 1977 Oct;37(1):127-34. doi: 10.1099/0022-1317-37-1-127.

DOI:10.1099/0022-1317-37-1-127
PMID:72129
Abstract

Electron microscopy of poliovirus particles and empty capsids under various conditions of specimen deposition and staining visualizes the dissociation products of these particles. The dissociation proceeds in steps; it begins with the expansion of particles and leads to the final product of the dissociation--a cluster of several sub-particles of equal size (approx. 100 A in diam.). A scheme of the dissociation is proposed on the basis of the observed intermediates.

摘要

在不同的标本沉积和染色条件下,对脊髓灰质炎病毒颗粒和空衣壳进行电子显微镜观察,可使这些颗粒的解离产物可视化。解离过程分阶段进行;首先是颗粒膨胀,最终导致解离产物——一簇大小相等的亚颗粒(直径约100埃)。根据观察到的中间体提出了解离方案。

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