Wibe Arne, Endreseth Birger Henning
Institutt for kreftforskning og molekylaer medisin, Det medisinske fakultet, Norges teknisk-naturvitenskapelige universitet, Trondheim.
Tidsskr Nor Laegeforen. 2007 Nov 15;127(22):2950-3.
Treatment of rectal cancer with total mesorectal excision has changed the national strategy for treatment of this condition during the last 15 years. The aim of this article was to describe contemporary standards of treatment for rectal cancer in Norway.
Reports on treatment results from the Norwegian Rectal Cancer Project form the basis for this article.
During the first six years (1993 - 1999) of the Norwegian Rectal Cancer Project; the rate of local recurrence was halfed (from 18 % to 9 %), the rate of anastomotic leakage decreased from 17 % to 8 % and radically operated patients (< 75 years) had a five-year overall survival rate of 71 %. Main factors for this improvement were most certainly implementation of total mesorectal excision, centralized treatment, establishing treatment teams of dedicated experts, improved preoperative work-up and tailored treatment.
在过去15年中，全直肠系膜切除术治疗直肠癌改变了该国针对这种疾病的治疗策略。本文旨在描述挪威直肠癌的当代治疗标准。
挪威直肠癌项目的治疗结果报告构成了本文的基础。
在挪威直肠癌项目的前六年（1993 - 1999年）；局部复发率减半（从18%降至9%），吻合口漏发生率从17%降至8%，接受根治性手术的患者（<75岁）五年总生存率为71%。这种改善的主要因素无疑是全直肠系膜切除术的实施、集中治疗、组建由专业专家组成的治疗团队、改善术前检查和个体化治疗。
