Hebert A A, Sigman E S, Levy M L
Department of Dermatology, University of Texas Medical School, Houston 77030.
J Am Acad Dermatol. 1991 Nov;25(5 Pt 1):805-8. doi: 10.1016/s0190-9622(08)80973-5.
Cefaclor is an oral semisynthetic cephalosporin that is popular in the treatment of infections in children. This drug has been associated with a serum sickness--like reaction characterized by an urticarial eruption, pruritus, arthritis, and/or arthralgias. We report 12 additional cases of cefaclor-related serum sickness--like reactions in children. All patients improved after discontinuation of the drug and no long-term complications resulted.
