Loo Sandra K, Humphrey Lorie A, Tapio Terttu, Moilanen Irma K, McGough James J, McCracken James T, Yang May H, Dang Jeff, Taanila Anja, Ebeling Hanna, Järvelin Marjo-Riitta, Smalley Susan L
University of California, Los Angeles, CA 90095, USA.
J Am Acad Child Adolesc Psychiatry. 2007 Dec;46(12):1594-604. doi: 10.1097/chi.0b013e3181575014.
The present study examined cognitive functioning in a population sample of adolescents with and without attention-deficit/hyperactivity disorder (ADHD) from the Northern Finland Birth Cohort 1986.
The sample consisted of 457 adolescents ages 16 to 18 who were assessed using a battery of cognitive tasks. Performance according to diagnostic group (control, behavior disorder, and ADHD) and sex was compared. Then, the effect of executive function deficit (EFD) was assessed by diagnostic group status on behavioral and cognitive measures.
When compared to non-ADHD groups, adolescents with ADHD exhibited deficits on almost all of the cognitive measures. The behavior disorder group obtained scores that were generally intermediate between the ADHD and control groups, but exhibited deficits in intelligence and executive function similar to the ADHD group. Approximately half the ADHD sample had EFD; however, the type and presence of EFDs were not differentially related to cognitive performance as a function of diagnosis.
These findings indicate that EFDs are more frequent in ADHD than control or behavior disorder groups. EFDs are a general risk factor for poor cognitive functioning across multiple domains, irrespective of diagnostic status.
本研究调查了1986年芬兰北部出生队列中患有和未患有注意力缺陷多动障碍(ADHD)的青少年群体样本的认知功能。
样本包括457名16至18岁的青少年,他们接受了一系列认知任务评估。比较了根据诊断组(对照组、行为障碍组和ADHD组)和性别的表现。然后,通过诊断组状态评估执行功能缺陷(EFD)对行为和认知测量的影响。
与非ADHD组相比,患有ADHD的青少年在几乎所有认知测量中都表现出缺陷。行为障碍组的得分通常介于ADHD组和对照组之间,但在智力和执行功能方面表现出与ADHD组相似的缺陷。大约一半的ADHD样本有EFD;然而,EFD的类型和存在与作为诊断函数的认知表现没有差异关系。
这些发现表明,EFD在ADHD中比对照组或行为障碍组更常见。EFD是多个领域认知功能差的一般风险因素,与诊断状态无关。