Silver Henry, Goodman Craig, Bilker Warren B, Knoll Gabriela, Gur Ruben, Povar Galina
Brain Behavior Laboratory, Sha'ar Menashe Mental Health Center, Hadera, Israel.
J Clin Exp Neuropsychol. 2007 Nov;29(8):823-30. doi: 10.1080/13803390601125963.
We studied the relationship between abstraction and other, more basic, cognitive functions in 78 schizophrenia patients and 57 healthy controls. Patients' performance was impaired compared to that of healthy individuals. Regression analysis showed significant contributions of task latency, spatial working memory, and verbal working memory to abstraction performance. The model explained 56.9% of the variance. The latency contribution included linear and quadratic components indicating optimal strategies for normal abstraction performance. Abnormal (suboptimal) processing strategies and working-memory dysfunctions predict impaired abstraction in schizophrenia. The model presented may enable differentiation between impaired and compensating components in schizophrenia patients with an abstraction deficit.
我们研究了78名精神分裂症患者和57名健康对照者的抽象能力与其他更基本的认知功能之间的关系。与健康个体相比，患者的表现受损。回归分析表明任务潜伏期、空间工作记忆和言语工作记忆对抽象能力表现有显著贡献。该模型解释了56.9%的方差。潜伏期贡献包括线性和二次成分，表明正常抽象能力表现的最佳策略。异常（次优）的加工策略和工作记忆功能障碍预示着精神分裂症患者的抽象能力受损。所提出的模型可能有助于区分抽象能力缺陷的精神分裂症患者中受损和代偿的成分。
