立克次氏体的基因组和代谢多样性。

The genomic and metabolic diversity of Rickettsia.

作者信息

Fuxelius Hans-Henrik, Darby Alistair, Min Chan-Ki, Cho Nam-Hyuk, Andersson Siv G E

机构信息

Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvägen 18C, S-752 36 Uppsala, Sweden.

出版信息

Res Microbiol. 2007 Dec;158(10):745-53. doi: 10.1016/j.resmic.2007.09.008. Epub 2007 Oct 4.

DOI:10.1016/j.resmic.2007.09.008

PMID:18031998

Abstract

Comparative genomics of Rickettsia and Orientia has revealed an exciting interplay between reductive evolutionary forces acting on metabolic genes in all species and proliferation of mobile genetic elements in some species. These contradictory evolutionary forces highlight the influence of chance, adaptation and host-cell exploitation during the evolution of intracellular bacteria.

摘要

立克次氏体属和东方体属的比较基因组学揭示了作用于所有物种代谢基因的还原性进化力量与某些物种中移动遗传元件增殖之间令人兴奋的相互作用。这些相互矛盾的进化力量凸显了细胞内细菌进化过程中偶然性、适应性和宿主细胞利用的影响。