赞比亚女性对杀微生物替代物的接受度。
Acceptability of microbicidal surrogates among Zambian women.
作者信息
Jones Deborah L, Weiss Stephen M, Chitalu Nadashi, Bwalya Violet, Villar Olga
机构信息
Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
出版信息
Sex Transm Dis. 2008 Feb;35(2):147-53. doi: 10.1097/OLQ.0b013e3181574dbf.
OBJECTIVES AND GOAL
This study assessed the acceptability after the use of vaginal lubricants as surrogates for microbicides among women in Zambia and the role of cultural factors as facilitators or impediments to their potential use for HIV risk reduction within the Zambian context.
STUDY DESIGN
HIV seronegative women (N = 301) recruited from the University Teaching Hospital HIV Voluntary Counseling and Testing Center were randomized into group, individual, or enhanced usual care arms. Participants attended pre- and post-HIV test counseling, followed by a 3-session, 2-hour once-a-month intervention introducing them to vaginal lubricants (2 types of gels, suppositories) in addition to male and female condoms. Supplies were offered at months 4 and 5; assessments were at baseline, 6, and 12 months.
RESULTS
At baseline, the majority of women reported minimal previous exposure to vaginal products and low levels of condom use. Participants' use of products was influenced by product characteristics and perceived partner acceptability; the majority of participants preferred drier products and suppository delivery systems. The basis for decisions regarding vaginal product acceptability changed over time and followed product exposure, and was greatly influenced by perceptions of partner acceptability.
CONCLUSION
Results illustrate the influence of male partners on Zambian seronegative women's preferences for microbicidal products, and the change in preferred characteristics over time.
目标与目的
本研究评估了赞比亚女性使用阴道润滑剂替代杀菌剂后的可接受性,以及文化因素在赞比亚背景下对其潜在用于降低艾滋病毒风险的促进或阻碍作用。
研究设计
从大学教学医院艾滋病毒自愿咨询与检测中心招募的301名艾滋病毒血清阴性女性被随机分为小组、个人或强化常规护理组。参与者在艾滋病毒检测前后接受咨询,随后进行为期3次、每月1次、每次2小时的干预,向她们介绍除男用和女用避孕套外的阴道润滑剂(2种凝胶、栓剂)。在第4个月和第5个月提供用品;评估在基线、第6个月和第12个月进行。
结果
在基线时,大多数女性报告以前很少接触阴道产品且避孕套使用率低。参与者对产品的使用受产品特性和伴侣可接受性认知的影响;大多数参与者更喜欢较干燥的产品和栓剂给药系统。关于阴道产品可接受性的决策依据随时间变化并随产品接触情况而改变,且受伴侣可接受性认知的极大影响。
结论
结果表明男性伴侣对赞比亚血清阴性女性对杀微生物产品偏好的影响,以及偏好特征随时间的变化。