Benecke Reiner, Dressler Dirk
Department of Neurology, Rostock University, Germany.
Disabil Rehabil. 2007 Dec 15;29(23):1769-77. doi: 10.1080/01421590701568262.
Axial truncal dystonia is characterized by an abnormal trunk posture often superimposed by myoclonic motor activities. Cervical dystonia is a motor syndrome characterized by abnormal head and neck posture due to tonic involuntary contractions in a certain set of muscles often superimposed by myoclonic or tremulous movements. Intramuscular injection of botulinum toxin is the first line treatment in cervical dystonia, in axial truncal dystonias botulinum toxin therapy is used only in mild forms. In this review the theoretical background, practical aspects and efficacy results especially in cervical dystonia are presented. Treatment of axial trunk dystonia is only briefly discussed at the beginning of this review.
轴性躯干肌张力障碍的特征是躯干姿势异常，常伴有肌阵挛性运动活动。颈部肌张力障碍是一种运动综合征，其特征是由于特定一组肌肉的强直性不自主收缩导致头颈部姿势异常，常伴有肌阵挛或震颤运动。肉毒杆菌毒素肌肉注射是颈部肌张力障碍的一线治疗方法，在轴性躯干肌张力障碍中，肉毒杆菌毒素疗法仅用于轻度病例。本综述介绍了理论背景、实际应用方面以及尤其是颈部肌张力障碍的疗效结果。本文仅在开头简要讨论了轴性躯干肌张力障碍的治疗。
