Demidov S V, Miasnikov V G, Chernushenko E F, Osipova L S
Probl Tuberk. 1991(12):52-4.
The effects of thymogen, thymalin and vilosen in combination with antituberculous drugs (isoniazid, streptomycin, rifampicin) were studied on 240 CBA mice with experimental tuberculosis. Thymus preparations supplemented to the complex treatment of experimental tuberculosis significantly increased their lifespan, contributed to a decrease in the index of spleen weight lung density and significantly increased the count of T lymphocytes and their proliferative activity as compared to those on antituberculous drugs alone. Thymogen was found to be the most effective in the complex treatment of experimental tuberculosis, whereas vilosen was the least. Thymogen plus vilosen proved to be the most beneficial combination of drugs.
研究了胸腺生成素、胸腺素和维洛辛与抗结核药物（异烟肼、链霉素、利福平）联合使用对240只患有实验性结核病的CBA小鼠的影响。在实验性结核病的综合治疗中添加胸腺制剂可显著延长小鼠寿命，有助于降低脾脏重量肺密度指数，并与单独使用抗结核药物相比，显著增加T淋巴细胞计数及其增殖活性。发现胸腺生成素在实验性结核病的综合治疗中最有效，而维洛辛最无效。胸腺生成素加维洛辛被证明是最有益的药物组合。
