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小儿肾积水肾引流报告的观察者间可重复性:一项大型合作研究。

Inter-observer reproducibility in reporting on renal drainage in children with hydronephrosis: a large collaborative study.

作者信息

Tondeur Marianne, De Palma Diego, Roca Isabel, Piepsz Amy, Ham Hamphrey

机构信息

Département des Radio-Isotopes, CHU Saint-Pierre, Rue Haute 322, Brussels, Belgium.

出版信息

Eur J Nucl Med Mol Imaging. 2008 Mar;35(3):644-54. doi: 10.1007/s00259-007-0641-9. Epub 2007 Nov 22.

Abstract

PURPOSE

The goal of this study was to evaluate the inter-observer reproducibility in reporting on renal drainage obtained during (99m)Tc MAG3 renography in children, when already processed data are offered to the observers.

METHODS

Because web site facilities were used for communication, 57 observers from five continents participated in the study. Twenty-three renograms, including furosemide stimulation and posterect postmicturition views, covering various patterns of drainage, were submitted to the observers. Images, curves and quantitative parameters were provided. Good or almost good drainage, partial drainage and poor or no drainage were the three possible responses for each kidney.

RESULTS

An important bias was observed among the observers, some of them more systematically reporting the drainage as being good, while others had a general tendency to consider the drainage as poor. This resulted in rather poor inter-observer reproducibility, as for more than half of the kidneys, less than 80% of the observers agreed on one of the three responses. Analysis of the individual cases identified some obvious causes of discrepancy: the absence of a clear limit between partial and good or almost good drainage, the fact of including or neglecting the effect of micturition and change of patient's position, the underestimation of drainage in the case of a flat renographic curve, and the difficulties of interpretation in the case of a small, not well functioning kidney.

CONCLUSION

There is an urgent need for better standardisation in estimating the quality of drainage.

摘要

目的

本研究的目的是评估当向观察者提供已处理的数据时,在报告儿童(99m)锝-巯基乙酰三甘氨酸(MAG3)肾动态显像中获得的肾引流情况时,观察者间的可重复性。

方法

由于使用网站设施进行交流,来自五大洲的57名观察者参与了该研究。向观察者提交了23份肾动态显像图,包括速尿激发试验及排尿后后位图像,涵盖了各种引流模式。提供了图像、曲线和定量参数。每个肾脏的三种可能反应为引流良好或几乎良好、部分引流以及引流差或无引流。

结果

在观察者之间观察到一个重要偏差,其中一些人更系统地将引流报告为良好,而另一些人总体上倾向于认为引流差。这导致观察者间的可重复性相当差,因为对于超过一半的肾脏,不到80%的观察者在三种反应中的一种上达成一致。对个别病例的分析确定了一些明显的差异原因:部分引流与良好或几乎良好引流之间没有明确界限、纳入或忽略排尿及患者体位变化的影响、肾动态显像曲线平坦时对引流的低估,以及肾脏小且功能不佳时的解释困难。

结论

迫切需要在评估引流质量方面进行更好的标准化。

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