Sakurai Susumu, Cui Renzhe, Tanigawa Takeshi, Yamagishi Kazumasa, Iso Hiroyasu
Department of Sleep Medicine, Graduate School of Comprehensive Human Sciences, and Institute of Community Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.
Alcohol Clin Exp Res. 2007 Dec;31(12):2053-8. doi: 10.1111/j.1530-0277.2007.00538.x.
Alcohol consumption as well as overweight is known to aggravate the severity of sleep-disordered breathing (SDB), but little is known about alcohol consumption in truck drivers. The aim of this study was to examine the relationship between alcohol consumption and SDB among truck drivers.
We conducted a cross-sectional study of 1,465 men aged 20-69 years who were registered with the Japanese Trucking Association. The 3% oxygen desaturation index (3%ODI) was selected as an indicator of SDB, representing the number of desaturation events per hour of recording time in which blood oxygen fell by > or =3% based on overnight pulse-oximetry. Participants completed a self-administered questionnaire including alcohol consumption on the same night for SDB assessment.
The prevalence of 3%ODI > or =5, > or =10, and > or =15/h was 25.4%, 11.1%, and 6.6% respectively. The multivariable odds ratios (OR) of 3%ODI > or = 10/h were 1.5(0.9-2.5) for 0.5 to <1.0 g of alcohol intake/kg and 3.4(1.8-6.6) for > or =1.0 g of alcohol intake/kg compared with non-drinkers. Similar associations with alcohol consumption were observed for 3%ODI > or =5 and > or =15/h. The relation between alcohol consumption (> or =1.0 g of alcohol intake/kg) and 3%ODI > or = 10/h tended to be more evident among men with body mass index (BMI) <23.4 kg/m(2) than those with BMI >or = 23.4 kg/m(2) [11.4 (3.2-41) vs. 1.2 (0.6-2.7), p = 0.18 for interaction]. A similar trend was observed for 3%ODI > or= 5/h.
The prevalence of undiagnosed SDB and the significant association of alcohol consumption with SDB severity emphasize the need for SDB screening and alcohol modification as well as weight control to prevent and control SDB among truck drivers.
众所周知，饮酒以及超重会加重睡眠呼吸紊乱（SDB）的严重程度，但对于卡车司机饮酒情况却知之甚少。本研究旨在探讨卡车司机饮酒与SDB之间的关系。
我们对1465名年龄在20 - 69岁、在日本卡车运输协会注册的男性进行了一项横断面研究。选择3%氧饱和度下降指数（3%ODI）作为SDB的指标，它代表基于夜间脉搏血氧饱和度测定法，每小时记录时间内血氧下降≥3%的饱和度下降事件数量。参与者完成一份自我管理问卷，包括当晚用于SDB评估的饮酒情况。
3%ODI≥5、≥10和≥15/小时的患病率分别为25.4%、11.1%和6.6%。与不饮酒者相比，酒精摄入量为0.5至<1.0克/千克体重时，3%ODI≥10/小时的多变量优势比（OR）为1.5（0.9 - 2.5）；酒精摄入量≥1.0克/千克体重时，OR为3.4（1.8 - 6.6）。对于3%ODI≥5和≥15/小时，也观察到与饮酒有类似关联。酒精摄入量≥1.0克/千克体重与3%ODI≥10/小时之间的关系，在体重指数（BMI）<23.4千克/米²的男性中往往比BMI≥23.4千克/米²的男性更明显[11.4（3.2 - 41）对1.2（0.6 - 2.7），交互作用p = 0.18]。对于3%ODI≥5/小时也观察到类似趋势。
未诊断出的SDB患病率以及饮酒与SDB严重程度之间的显著关联，强调了对卡车司机进行SDB筛查、控制饮酒以及控制体重以预防和控制SDB的必要性。
