Novikov A I, Ivanov A E, Golovniak I E, Baeva L B, Levitskiĭ E R
Ter Arkh. 1991;63(12):107-10.
Biopsy specimens of the bone were examined and then subjected to morphometry in 49 patients with terminal renal failure. 43 patients were on chronic hemodialysis and 6 had undergone renal transplantation. Histomorphometry permitted calculating the relative area of the bone girdles in the preparation (in %), the relative resorption area (in %), and the osteocyte count per mm2 bone girdle. It is concluded that if the area of the bone girdle in the preparation is less than 23.8%, the patient on hemodialysis may be diagnosed as having dialysis osteomalacia. The reduction of the relative reabsorption area in patients with dialysis osteomalacia is insignificant and can be used as an auxiliary sign in differential diagnosis of renal osteopathies in patients on dialysis.
对49例终末期肾衰竭患者的骨活检标本进行了检查，然后进行形态计量学分析。其中43例患者接受慢性血液透析，6例接受了肾移植。组织形态计量学可以计算标本中骨环的相对面积（%）、相对吸收面积（%）以及每平方毫米骨环中的骨细胞数量。得出的结论是，如果标本中骨环面积小于23.8%，接受血液透析的患者可能被诊断为患有透析性骨软化症。透析性骨软化症患者相对重吸收面积的降低不明显，可作为透析患者肾性骨病鉴别诊断的辅助指标。
