Rudnick Emily F, Mitchell Ron B
Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, Children's Hospital and Regional Medical Center, The University of Washington School of Medicine, Seattle, WA 98105, USA.
Otolaryngol Head Neck Surg. 2007 Dec;137(6):873-7. doi: 10.1016/j.otohns.2007.08.006.
To study long-term changes in quality-of-life (QOL) in children after surgery for chronic sinonasal disease.
Prospective, nonrandomized.
Caregivers completed the SN-5 QOL instrument before surgery. Children underwent either adenoidectomy or endoscopic sinus surgery (ESS). Caregivers then completed a survey <6 months (short-term) and between six and 24 months after surgery (long-term). Scores were compared using a paired t test.
Twenty-two children were enrolled (mean age, 5.7 years). The majority (59%) of children underwent ESS. The mean preoperative total score was 25.6. Postoperatively, the mean total score was 11.7 at short-term (P < 0.0001) and 11.5 at long-term follow-up (P < 0.0001). Short- and long-term postoperative scores for all domains were significantly different from preoperative scores. In the long-term scores, the domain with the greatest change was "emotional distress" (SRM 1.9) and with the smallest change was "allergy symptoms" (SRM 1.0). There were no significant differences between children who underwent adenoidectomy compared with ESS.
After adenoidectomy or ESS, caregivers observe a long-term improvement in QOL of children with sinonasal disease.
研究慢性鼻窦疾病患儿手术后生活质量（QOL）的长期变化。
前瞻性、非随机研究。
护理人员在手术前完成SN-5生活质量量表。儿童接受腺样体切除术或鼻内镜鼻窦手术（ESS）。护理人员随后在术后<6个月（短期）以及术后6至24个月（长期）完成一项调查。使用配对t检验比较得分。
纳入22名儿童（平均年龄5.7岁）。大多数（59%）儿童接受了ESS。术前平均总分是25.6。术后，短期平均总分是11.7（P<0.0001），长期随访时为11.5（P<0.0001）。所有领域的术后短期和长期得分与术前得分均有显著差异。在长期得分中，变化最大的领域是“情绪困扰”（标准化反应均值1.9），变化最小的是“过敏症状”（标准化反应均值1.0）。接受腺样体切除术的儿童与接受ESS的儿童之间无显著差异。
腺样体切除术或ESS后，护理人员观察到鼻窦疾病患儿的生活质量有长期改善。
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