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儿童慢性鼻-鼻窦炎临床治疗指南。

Clinical Guidelines on Chronic Rhinosinusitis in Children.

机构信息

Department of Head and Neck Surgery, David Geffen School of Medicine at University of California Los Angeles, 10833 Le Conte Ave, CHS 62-237, Los Angeles, CA, 90095, USA.

Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

出版信息

Curr Allergy Asthma Rep. 2019 Feb 22;19(2):14. doi: 10.1007/s11882-019-0845-7.

DOI:10.1007/s11882-019-0845-7
PMID:30796536
Abstract

PURPOSE OF REVIEW

Pediatric chronic rhinosinusitis (CRS) is a prevalent problem that can elude diagnosis. In addition, given the burgeoning interest in pediatric sinonasal disease, treatment modalities are constantly evolving.

RECENT FINDINGS

The diagnosis of pediatric CRS is primarily based on clinical history and signs supported by objective findings (i.e., nasal endoscopy and/or computed tomography (CT) imaging). Cultures are indicated in patients who have not responded to medical therapy or have significant comorbidities. Nasal saline irrigation, nasal saline spray, and oral antibiotics are currently recommended for initial medical management. In children with CRS who have failed medical therapy, a stepwise approach to surgical intervention can lead to significant improvements in quality of life. This review provides an overview of the current guidelines and recent literature regarding the diagnosis, microbiology, and treatment options of CRS in the pediatric population.

摘要

目的综述

小儿慢性鼻-鼻窦炎(CRS)是一种普遍存在的问题,可能难以诊断。此外,鉴于小儿鼻-鼻窦疾病日益受到关注,治疗方法也在不断发展。

最近的发现

小儿 CRS 的诊断主要基于临床病史和体征,并辅以客观发现(即鼻内镜和/或计算机断层扫描(CT)成像)。对于未对药物治疗有反应或存在严重合并症的患者,应进行培养。目前推荐使用鼻腔盐水冲洗、鼻腔盐水喷雾和口服抗生素进行初始药物治疗。对于药物治疗失败的小儿 CRS 患者,手术干预的逐步方法可显著提高生活质量。本文综述了小儿 CRS 的当前指南和最新文献,内容涉及小儿 CRS 的诊断、微生物学和治疗选择。

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Clinical Guidelines on Chronic Rhinosinusitis in Children.儿童慢性鼻-鼻窦炎临床治疗指南。
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引用本文的文献

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Rhinosinusitis: Evidence and experience - 2024.鼻窦炎:证据与经验 - 2024年
Braz J Otorhinolaryngol. 2025 May 19;91(5):101595. doi: 10.1016/j.bjorl.2025.101595.
2
Clinical Characteristics of Pediatric Chronic Rhinosinusitis: A Nationwide Retrospective Multicenter Study.儿童慢性鼻-鼻窦炎的临床特征:一项全国性回顾性多中心研究
J Rhinol. 2025 Mar;32(1):28-35. doi: 10.18787/jr.2024.00040. Epub 2025 Mar 21.
3
[Expert consensus on the diagnosis and treatment of chronic sinusitis in children].[儿童慢性鼻窦炎诊断和治疗专家共识]

本文引用的文献

1
The Burden and Visit Prevalence of Pediatric Chronic Rhinosinusitis.小儿慢性鼻-鼻窦炎的负担及就诊患病率
Otolaryngol Head Neck Surg. 2017 Dec;157(6):1048-1052. doi: 10.1177/0194599817721177. Epub 2017 Jul 25.
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Finding clinical efficacy with balloon sinus dilation in pediatric chronic rhinosinusitis patients.
Int Forum Allergy Rhinol. 2017 Jun;7(6):629-630. doi: 10.1002/alr.21933. Epub 2017 Mar 20.
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Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis.鼻内用类固醇与安慰剂或不干预治疗慢性鼻-鼻窦炎的比较
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Dec;38(12):1091-1099. doi: 10.13201/j.issn.2096-7993.2024.12.001.
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Association of Childhood IgA Vasculitis With Allergic Rhinitis and Chronic Rhinosinusitis.儿童IgA血管炎与变应性鼻炎和慢性鼻-鼻窦炎的关联。
Kidney Int Rep. 2024 Jul 6;9(9):2759-2766. doi: 10.1016/j.ekir.2024.07.003. eCollection 2024 Sep.
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Pediatric Odontogenic Sinusitis: A Systematic Review.小儿牙源性鼻窦炎:一项系统评价
J Clin Med. 2024 Apr 11;13(8):2215. doi: 10.3390/jcm13082215.
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Clinical Characteristics of Rhinosinusitis in Children in a Tertiary Care Center.三级医疗中心儿童鼻窦炎的临床特征
Cureus. 2023 Dec 28;15(12):e51236. doi: 10.7759/cureus.51236. eCollection 2023 Dec.
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Application of nasal irrigation in the treatment of chronic rhinosinusitis.鼻腔冲洗在慢性鼻-鼻窦炎治疗中的应用
Asia Pac Allergy. 2023 Dec;13(4):187-198. doi: 10.5415/apallergy.0000000000000120. Epub 2023 Dec 8.
8
Orally administered Chinese herbal therapy to assist post-surgical recovery for chronic rhinosinusitis-A systematic review and meta-analysis.中药口服疗法辅助慢性鼻-鼻窦炎术后康复:系统评价和荟萃分析。
PLoS One. 2023 Oct 5;18(10):e0292138. doi: 10.1371/journal.pone.0292138. eCollection 2023.
9
Allergic Rhinitis as an Independent Risk Factor for Postoperative Recurrence of Children Chronic Sinusitis.变应性鼻炎作为儿童慢性鼻窦炎术后复发的独立危险因素
Children (Basel). 2023 Jul 12;10(7):1207. doi: 10.3390/children10071207.
10
Associations of Microbial Diversity with Age and Other Clinical Variables among Pediatric Chronic Rhinosinusitis (CRS) Patients.小儿慢性鼻-鼻窦炎(CRS)患者微生物多样性与年龄及其他临床变量的相关性
Microorganisms. 2023 Feb 7;11(2):422. doi: 10.3390/microorganisms11020422.
Cochrane Database Syst Rev. 2016 Apr 26;4(4):CD011996. doi: 10.1002/14651858.CD011996.pub2.
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Am J Rhinol Allergy. 2015 Nov-Dec;29(6):414-20. doi: 10.2500/ajra.2015.29.4238.
5
What is the role of the adenoid in pediatric chronic rhinosinusitis?腺样体在小儿慢性鼻-鼻窦炎中起什么作用?
Laryngoscope. 2015 Jun;125(6):1282-3. doi: 10.1002/lary.25090. Epub 2014 Dec 18.
6
Clinical consensus statement: pediatric chronic rhinosinusitis.临床共识声明:儿童慢性鼻-鼻窦炎
Otolaryngol Head Neck Surg. 2014 Oct;151(4):542-53. doi: 10.1177/0194599814549302.
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Growth velocity reduced with once-daily fluticasone furoate nasal spray in prepubescent children with perennial allergic rhinitis.对于患有常年性变应性鼻炎的青春期前儿童,每日一次糠酸氟替卡松鼻喷雾剂会降低生长速度。
J Allergy Clin Immunol Pract. 2014 Jul-Aug;2(4):421-7. doi: 10.1016/j.jaip.2014.04.008. Epub 2014 May 21.
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Topical anti-infective sinonasal irrigations: update and literature review.局部抗感染性鼻窦冲洗:最新进展与文献综述
Am J Rhinol Allergy. 2014 Jan-Feb;28(1):29-38. doi: 10.2500/ajra.2014.28.3988.
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Curr Opin Otolaryngol Head Neck Surg. 2014 Feb;22(1):27-33. doi: 10.1097/MOO.0000000000000018.
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Compliance and efficacy of saline irrigation in pediatric chronic rhinosinusitis.生理盐水冲洗在小儿慢性鼻-鼻窦炎中的依从性和疗效
Auris Nasus Larynx. 2014 Feb;41(1):46-9. doi: 10.1016/j.anl.2013.07.008. Epub 2013 Aug 8.