[丁基卡普他对大鼠肝脏线粒体膜氧化磷酸化及多酶系统活性的影响]
[The effect of butylcaptax on oxidative phosphorylation and the activity of multienzyme systems of the mitochondrial membranes in the rat liver].
作者信息
Mirakhmedov A K, Rustamov R D, Almatov K T, Agzamov Kh
出版信息
Tsitologiia. 1991;33(4):89-94.
PMID:1803706
Abstract
The oxidative phosphorylation and the activity of polyenzymatic systems in the rat liver mitochondrial membranes were studied upon a 5 day administration to rats of butylcaptax in the dose of 1/10 LD50. It is established that butylcaptax led to significant disturbances in the system of oxidative phosphorylation and in the transfer of electrons in the rat liver mitochondrial respiratory chain.
摘要
在以1/10 LD50的剂量给大鼠连续5天施用丁硫克百威后，对大鼠肝线粒体膜中的氧化磷酸化和多酶系统活性进行了研究。结果表明，丁硫克百威导致大鼠肝线粒体呼吸链中的氧化磷酸化系统和电子传递出现显著紊乱。
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