Kupnovyts'ka I H, Chuklin S M
Vrach Delo. 1991 Oct(10):87-9.
A study is presented of the effect of a new native calcium antagonist foridon on the course of the disease central and peripheral hemodynamics, fatty metabolism, lipid peroxidation intensity, activity of ceruloplasmin and catalase, iron and chromium saturation of transferrin, content of cyclic nucleotides in thrombocytes, the state of cellular immunity and the number of circulating immune complex in 30 patients with advancing and stable exertion stenocardia (control--30 analogous patients treated by phynoptin and corinfar). It was established that foridon produced a positive effect on the intensity of the pain syndrome, hemodynamics, degree of lipid peroxidation, content of cyclic nucleotides and immune status of stenocardia patients.
一项关于新型天然钙拮抗剂福立多(foridon)对30例进行性和稳定性劳力型心绞痛患者疾病进程影响的研究,涉及中心和外周血流动力学、脂肪代谢、脂质过氧化强度、铜蓝蛋白和过氧化氢酶活性、转铁蛋白的铁和铬饱和度、血小板中环核苷酸含量、细胞免疫状态及循环免疫复合物数量(对照组为30例接受心可定和冠心平治疗的类似患者)。结果表明,福立多对心绞痛患者的疼痛综合征强度、血流动力学、脂质过氧化程度、环核苷酸含量及免疫状态产生了积极影响。