Kaminsky Radoslav, Kallweit Stephan, Weber Hans-Joachim, Claessens Tom, Jozwik Krzysztof, Verdonck Pascal
Institute Biomedical Technology (IBiTech), Ghent University, Ghent, Belgium.
Artif Organs. 2007 Dec;31(12):869-79. doi: 10.1111/j.1525-1594.2007.00471.x.
The number of candidates waiting for a heart valve replacement rises yearly. Even though there is a trend toward implantation of biological valves or reconstruction, the prosthetic heart valves (PHVs) are still commonly used for implantation or as a part of cardiac assist devices in many countries worldwide. However, the hemodynamic consequences of these valves are still not completely understood. Unfortunately, these devices currently do not perform sufficiently on a long-term basis and may lead to several complications, many of them are related to fluid mechanical aspects. A novel method, stereoscopic high-speed particle image velocimetry, was applied to quantify all three velocity components behind a PHV in detailed time domain. In this study, we compared clinically used bileaflet aortic prosthetic (ATS) valve and monoleaflet prototype of tilting disk PHV. The absolute velocities calculated out of two and three velocity components were compared to each other to estimate the overall difference in the desired region of interest. The most significant discrepancies between the two- and three-component absolute velocities were found at the regions of Valsalva sinuses and in a major jet stream of monoleaflet PHV.
等待心脏瓣膜置换的患者数量逐年增加。尽管存在植入生物瓣膜或进行重建的趋势，但人工心脏瓣膜（PHV）在世界许多国家仍普遍用于植入或作为心脏辅助装置的一部分。然而，这些瓣膜的血流动力学后果仍未完全了解。不幸的是，这些装置目前在长期使用中表现不佳，可能会导致多种并发症，其中许多与流体力学方面有关。一种新颖的方法，即立体高速粒子图像测速技术，被应用于在详细的时域内量化PHV后方的所有三个速度分量。在本研究中，我们比较了临床使用的双叶主动脉人工瓣膜（ATS）和倾斜盘式PHV的单叶原型。将由两个和三个速度分量计算出的绝对速度相互比较，以估计感兴趣的目标区域的总体差异。在主动脉窦区域和单叶PHV的主要射流中发现了双分量和三分量绝对速度之间最显著的差异。
