躯体形式障碍的生物学基础：病理生理学的重要性
A biological substrate for somatoform disorders: importance of pathophysiology.
作者信息
Dimsdale Joel E, Dantzer Robert
机构信息
Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, USA.
出版信息
Psychosom Med. 2007 Dec;69(9):850-4. doi: 10.1097/PSY.0b013e31815b00e7.
Abstract
Somatoform disorders are troubling to both patients and physicians. The diagnosis regrettably relies on the presence of subjective distress in the absence of objective findings. As a result, there is always the possibility that a diagnosis will be "missed." There is a clear underlying physiology of distress, which implies that there is a two-way street--both psychosomatic and somatopsychic in terms of production and experience of somatoform symptoms. Studies on communication pathways from the immune system to the brain provide exciting new information on the pathophysiology of inflammation-associated symptoms.
摘要
躯体形式障碍对患者和医生来说都很棘手。遗憾的是，诊断依赖于主观痛苦的存在而缺乏客观发现。因此，总是存在漏诊的可能性。痛苦有着明确的潜在生理机制，这意味着存在一条双向通道——就躯体形式症状的产生和体验而言，既有心身方面的，也有身心方面的。关于从免疫系统到大脑的通信通路的研究为炎症相关症状的病理生理学提供了令人兴奋的新信息。
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