[局限性肌张力障碍和面部痉挛：肉毒杆菌A毒素治疗]
[Focal dystonias and facial hemispasm: treatment with botulinum A toxin].
作者信息
Astarloa R, Morales B, Sánchez V, Peñafiel N, Rábano J, Oliván J, García de Yébenes J
机构信息
Servicio de Neurología, Fundación Jiménez Díaz, Madrid.
出版信息
Arch Neurobiol (Madr). 1991 Sep-Oct;54(5):210-7.
We report the results of the treatment of 80 patients with various idiopathic focal dystonia and essential hemifacial spasm with Botulinum A toxin. A statistically significant improvement was obtained in our 34 patients with blepharospasm, 19 patients with hemifacial spasm, 59% of 22 patients with cervical dystonia and 60% of 5 patients with hand dystonia. Mean duration of the benefit of each injection was 15.3, 16.3, 7.6 and 8.7 weeks respectively. Adverse effects were local and transient. We concluded that botulinum A toxin is a safe and effective therapy for patients with focal dystonia and hemifacial spasm.
我们报告了用A型肉毒杆菌毒素治疗80例各种特发性局灶性肌张力障碍和原发性半面痉挛患者的结果。我们的34例眼睑痉挛患者、19例半面痉挛患者、22例颈部肌张力障碍患者中的59%以及5例手部肌张力障碍患者中的60%均获得了具有统计学意义的改善。每次注射的平均获益持续时间分别为15.3周、16.3周、7.6周和8.7周。不良反应为局部且短暂的。我们得出结论，A型肉毒杆菌毒素是治疗局灶性肌张力障碍和半面痉挛患者的一种安全有效的疗法。
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