Małkowska-Zwierz W, Garliński P, Zukowska M, Zabuska K, Wartanowicz M, Kleniewska D, Niemirowska H, Izdebska Z, Roszkowski W, Wróblewski T
Medical Center of Postgraduate Education, Warsaw, Poland.
Arch Immunol Ther Exp (Warsz). 1991;39(1-2):109-15.
The influence of vit. E treatment on metabolic and bactericidal granulocyte activity in patients with recurrent infections was studied by chemiluminescence and phagocytosis assays. Vit. E serum level was significantly diminished before therapy. Six weeks supplementation with 200-300 mg/day of vit. E resulted in improvement of clinical status and normalisation of alpha-tocopherol serum level. Bactericidal activity of granulocytes was lower in patients than in the respective controls and it slightly rose after vit. E therapy. Before, therapy, patients granulocytes showed metabolic activity above or within the control range. Vit. E treatment increased, had no effect or decreased granulocyte metabolic activity, but never below the control range.
通过化学发光和吞噬作用测定法，研究了维生素E治疗对复发性感染患者代谢和杀菌粒细胞活性的影响。治疗前维生素E血清水平显著降低。每天补充200 - 300毫克维生素E，持续六周，可改善临床状况并使α-生育酚血清水平恢复正常。患者粒细胞的杀菌活性低于相应对照组，维生素E治疗后略有上升。治疗前，患者粒细胞显示出高于或在对照范围内的代谢活性。维生素E治疗使粒细胞代谢活性增加、无影响或降低，但从未低于对照范围。
