硝基粒细胞生成素依赖性抗体合成抑制。I. 人体体外研究。
Nitrogranulogen-dependent inhibition of antibody synthesis. I. In vitro studies in man.
作者信息
Wasik M, Stepień-Sopniewska B, Kozakiewicz A, Górski A
机构信息
Department of Immunology, Medical School, Warsaw.
出版信息
Arch Immunol Ther Exp (Warsz). 1991;39(1-2):117-20.
PMID:1804040
Abstract
Nitrogranulogen causes a comparable suppression of immunoglobulin synthesis by human lymphocytes in vitro as a standard alkylating agent, 4-hydro-peroxycyclophosphamide. Mixed lymphocyte culture reaction-elicited T and B cell responses are especially sensitive to the agent. The immunosuppressive activity of NTG is enhanced by a thymic hormone (TFX).
摘要
硝基颗粒原在体外对人淋巴细胞免疫球蛋白合成的抑制作用与标准烷化剂4-氢过氧环磷酰胺相当。混合淋巴细胞培养反应引发的T细胞和B细胞反应对该药物尤为敏感。胸腺激素（TFX）可增强NTG的免疫抑制活性。
Zotero 插件