Kiraly Michael, Kiraly Stephen J
Faculty of Medicine, University of Toronto.
ScientificWorldJournal. 2007 Nov 12;7:1768-76. doi: 10.1100/tsw.2007.269.
Brain injuries are too common. Most people are unaware of the incidence of and horrendous consequences of traumatic brain injury (TBI) and mild traumatic brain injury (MTBI). Research and the advent of sophisticated imaging have led to progression in the understanding of brain pathophysiology following TBI. Seminal evidence from animal and human experiments demonstrate links between TBI and the subsequent onset of premature, psychiatric syndromes and neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Objectives of this summary are, therefore, to instill appreciation regarding the importance of brain injury prevention, diagnosis, and treatment, and to increase awareness regarding the long-term delayed consequences following TBI.
脑损伤十分常见。大多数人并未意识到创伤性脑损伤（TBI）和轻度创伤性脑损伤（MTBI）的发病率及其可怕后果。研究以及先进成像技术的出现，使人们对TBI后脑病理生理学的理解取得了进展。来自动物和人体实验的重要证据表明，TBI与过早出现的精神综合征和神经退行性疾病（包括阿尔茨海默病（AD）和帕金森病（PD））的后续发病之间存在关联。因此，本综述的目的是让人们认识到脑损伤预防、诊断和治疗的重要性，并提高对TBI后长期延迟后果的认识。
