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[氙气——理想的麻醉剂?]

[Xenon--the ideal anaesthetic agent?].

作者信息

Bein Berthold, Höcker Jan, Scholz Jens

机构信息

Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2007 Nov;42(11):784-91. doi: 10.1055/s-2007-1003591.

Abstract

The noble gas xenon, besides its anaesthetic and analgesic properties, shows many characteristics of an ideal anaesthetic agent. However, due to high production costs, its application is limited In daily clinical routine. Recent studies suggested not only outstanding haemodynamic stability and rapid emergence from anaesthesia, but also xenon's capacity to mediate protection against ischaemic damage in various organs and tissues. Since xenon is devoid of toxicity and relevant side effects, it could be beneficial at least in a subset of patients at high risk, and xenon therefore may become a reasonable alternative in this patient population.

摘要

惰性气体氙,除了具有麻醉和镇痛特性外,还展现出理想麻醉剂的诸多特征。然而,由于生产成本高昂,其在日常临床实践中的应用受到限制。近期研究表明,氙不仅具有出色的血流动力学稳定性和快速苏醒特性,还具备介导对各器官和组织缺血性损伤的保护能力。鉴于氙无毒且无相关副作用,至少对一部分高危患者可能有益,因此氙在这类患者群体中可能成为一种合理的替代选择。

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