Department of Anaesthesiology, University Hospital of Aachen, Aachen, Germany.
Eur J Anaesthesiol. 2010 Jul;27(7):660-5. doi: 10.1097/EJA.0b013e328336ec3b.
Stable haemodynamics and its cardioprotective and neuroprotective properties favour xenon as an ideal but expensive anaesthetic agent. The aim of this study was to optimize a semi-closed anaesthesia circuit for xenon anaesthesia with respect to economics and patient safety.
A semi-closed nonrebreathing circuit was compared with a closed anaesthesia circuit. In 12 landrace pigs, we compared eight different wash-in procedures affecting xenon consumption. Additionally, the maintenance of anaesthesia was analysed with regard to minimizing xenon consumption.
The current study showed that, by optimization of the electronic regulation of the wash-in procedure for xenon anaesthesia, the consumption of the valuable gas can be reduced by up to 75% in a semi-closed circuit. The additional maintenance of anaesthesia under low flow conditions by coupling the xenon flow to the oxygen consumption is the most effective way to technically reduce the amount of xenon needed for anaesthesia.
稳定的血流动力学及其心脏保护和神经保护特性使氙气成为一种理想但昂贵的麻醉剂。本研究旨在针对经济性和患者安全性优化半封闭氙气麻醉回路。
将半封闭非再呼吸回路与封闭麻醉回路进行比较。在 12 头长白猪中，我们比较了 8 种不同的影响氙气消耗的洗入程序。此外，还分析了维持麻醉以尽量减少氙气消耗的情况。
本研究表明，通过优化氙气麻醉洗入程序的电子调节，在半封闭回路中，有价值气体的消耗可减少多达 75%。通过将氙气流与耗氧量耦合来在低流量条件下维持麻醉是从技术上减少麻醉所需氙气量的最有效方法。
