Laudi Sven, Busch Thilo, Bercker Sven, Donaubauer Bernd, Kaisers Udo
Klinik und Poliklinik für Anästhesiologie und Intensivtherapie des Universitätsklinikums Leipzig.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2007 Nov;42(11):794-9. doi: 10.1055/s-2007-1003592.
The treatment of acute lung injury is one of the most challenging tasks in intensive care medicine. Conventional therapeutic options cover lung protective mechanical ventilation with low tidal volumes and adequate PEEP, restrictive fluid management, prone positioning, and early recruitment maneuvers. These options should be used in parallel and should be accompanied by a suitable anti-infective therapy. In cases of refractory hypoxemia, inhaled nitric oxide offers in most patients a successful rescue option. In specialized centers the application of ECMO remains as a final ultima ratio.
急性肺损伤的治疗是重症监护医学中最具挑战性的任务之一。传统的治疗方法包括采用低潮气量和适当呼气末正压通气的肺保护性机械通气、限制性液体管理、俯卧位通气以及早期肺复张手法。这些方法应并行使用，并应辅以适当的抗感染治疗。在难治性低氧血症的情况下，吸入一氧化氮对大多数患者而言是一种成功的挽救措施。在专业中心，体外膜肺氧合（ECMO）的应用仍是最后的终极手段。
